Just moved here a week ago. Housing is the biggest pain in the butt, had a Craigslist sublet fall through on me twice. Now looking for a sublet in October.... It's a pain.
I've found there are a ton of networking events (106 miles, Hackers and Founders, etc) on meetup. Also if you find an interesting company just email the CEO. In the Mission district of SF right now and I really like it. The tech scene here is really hot, if you've got skills just email the company you're interested in, they'll talk to you.