I found your question interesting and found this article: https://www.jstor.org/stable/27739679

> The advent of automobile use in the early 20th century brought about a measurable rise in total numbers of highway deaths and injuries. However, the automobile's toll on human life and limb was probably not extravagantly greater than the toll exacted by the combination of steam- and horse-driven travel methods it displaced

From skimming the article, it seems like motor vehicle fatalities in NYC in the 1990s were similar to total traffic fatalities in the early 1900s, even though the population almost doubled.

I'm assuming motor vehicle fatalities includes pedestrians hit by motor vehicles. There could still be additional deaths today from things like streetcars, horses, or ox carts, but I feel like those would be low.