We use it exclusively for the soon to be released 1.0 version of Zotonic. See: https://test.zotonic.com (running on a 4.99 euro Hetzner vps).
We developed an independent support javascript library called Cotonic (https://cotonic.org) to handle pub/sub via MQTT. This library can also connect to other compliant MQTT brokers. Because MQTT is fairly simple protocol, it is fairly easy to integrate in existing frameworks. Here is an example chat application (https://cotonic.org/examples/chat) which uses the open Eclipse broker.