mRNA vaccine-induced antibodies more effective than natural immunity vs. Covid

Natural immunity makes less for the spike, but more overall, both in breadth of type and total number.

Artificially limiting the count to one type of antibody is like claiming to be richer than Warren Buffet because you have more cash in your wallet than him in line at McDonalds, and ignoring the fact that your wallet contains your total net wealth.

Worse, the vaccinated samples were all gathered by mid-March 2021, and except for three people, all were gathered within 40 days of vaccination. But the median time from symptoms for those who were previously infected was over two hundred days.

This difference alone hopelessly confounds any stated conclusion, yet they've buried this essential information in the supplemental materials (ST1 & 2). This paper is bad.

The article merely says Thus, our data indicates that mRNA vaccination may generate more neutralizing RBD antibodies than natural immunity.

It makes no mention of how long it lasts. So, it is entirely possible that mRNA vaccine produce more antibodies but they diminish pretty quickly. While, an infection produces fewer antibodies, relatively speaking of course, but they last longer. Yes?

You can't even say simply that one vaccine is better or worse or than another because now you have to say better or worse at what exactly.

Vaccine give more protection but for a shorter period of time.

It works by infecting your body with an adenovirus that allegedly can’t reproduce. When it infects your cells, it forces them to produce spike protein. Your body then creates antibodies against these proteins.

If you have an immunity to a similar adenovirus, most of the vaccine will be killed off. Likewise, after being vaccinated, your body develops an immunity to the vaccine.

The only differences with the mRNA vaccine in antibodies would arise from slightly different spike proteins being generated by the cells. The rest of the antibodies are gained from the rest of the COVID virus, but those don’t exist in the adenovirus, so there’s no way it uses creating them. At most, the antibodies against the adenovirus might have some little incidental effect. If it were a large effect then we’d expect tons of people to have immunity and covid would not be novel.

Finally I’ll add that J&J is hardly “traditional”. Despite the marketing, only two other viral vector vaccines have been created for humans —- they were both emergency Ebola vaccines released in 2016 and 2019 respectively. 3-5 years and two emergency vaccines is hardly what anyone would believe traditional means.

Why does this make them idiots? Maybe they reviewed the trial data and observed the increased all-cause mortality in the vaccinated group, looked at the history of rushed vaccines, looked at the list of unknowns regarding mRNA technology, and decided "no thanks".

Indeed, hindsight is proving those "idiots" to be quite the opposite.

“The data demonstrate COVID-19 mRNA vaccines effectively induce spike antigen specific IgG and IgA and highlight marked differences in their persistence in serum.“

Covid is the disease and this study does not address disease directly.