I would highly suggest that your friend contact the National Federation of the Blind. They have a Computer Science Council, and a mailing list at https://www.nfbnet.org/mailman/listinfo/nfbcs_nfbnet.org which is full of Blidn technologists who have been able to be effective at work and in life through the use of assistive technology of various stripes. This is a great place to find information.

I have two very close friends who are Blind, one is an SRE and the other is a data scientist, both use different types of assistive technology but have found that Linux and MacOS tend to work better than Windows, partly due to the availability and usefulness of the command line which is a better UI for a Blind user than a GUI. There are now fantastic screen readers which are free and/or open source available on these OSes.