Mess is subjective. I've been using the same stable UI framework for 20 years. Today's junior frontend devs were in diapers when I started using Windows Forms and it hasn't ever been broken or required rewrites. I don't think web developers even realize this is possible.

The biggest choice is deciding how much you like technologies from the Windows team. Personally, I stay away from them. With the exception of the very oldest technologies (Win32 and COM), tech from the Windows team has less longevity than technologies from DevDiv. That means yes to Blazor, WinForms, and WPF, and no to UWP and WinRT.

Note that Blazor has a server-side edition. Most production Blazor usage is not WebAssembly-based at this point in time.