PSA: Pi 4 + M.2 SATA SSD + USB3 adapter is blisteringly fast. No micro SD card needed any more. Runs Ubuntu x64 and Docker.

Even better with a heat-dissipating case with an integrated M.2 SATA port in the bottom, like the Argon ONE M.2.

I use mine to run multiple .NET 6 microservices, and it's replaced an entire HP Microserver. The entire Pi setup will have paid for itself in under a year in energy savings alone.