* Note: this is only valid for the time of writing. We cannot guarantee these libraries will still represent the state of the art past this date.
Yarn and NPM has been around for a long time. Yarn 1 used to be the better choice since NPM stagnated, now they're a bit more equal.
Typescript has been around for a long time. So has ES6 modules. Same for Jest and Mocha.
The only thing that is changing somewhat are the bundlers and build tools (thankfully, they've been the weakest part of FE dev for a long time).
I've kept up with frontend for many years. There really isn't all that much "fatigue" if one actually understands what the tools do and the niches they fill.