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That said, this is pretty poorly designed. I also had no clue what to do for the first few seconds after I clicked the link. It was only at slide 38/41 that I noticed the tiny, hidden controls on the very bottom blending into my status bar.

I didn't even notice those. Fortunately, I've worked with systems like S5 slideshows, and this looked a lot like a slideshow (no scroll bar, large text, numeric fragment in the URL).

Usability could definitely be better, but I will admit to writing up similarly boring slides in the past.

Compare this slideshow to the basic S5 slideshow at http://meyerweb.com/eric/tools/s5/s5-intro.html . A simple CSS template could solve the usability problem here.

I wonder why 280slides never really took off. This still seems like an unsolved problem (hosting slides online)

Slideshare and Scribd: both allow you to use the program you already know (Keynote or PowerPoint, most likely) that's also a native app with lots of powerful functionality.

And on an iPad, nothing works.

I don't know if it's Opera being smart, but space works for me as well.