Why do we absolve some people of guilt for being a product of their genes and environment and not others? Where do you draw the line? It would seem that "they couldn't help it" just as much as the people that you describe.
If a person with Tourette's said profanities to you during your Zoom meeting, would you hold them equally responsible as a person not having it? No, because it's a symptom and you assume it is out of their control and they didn't have a malicious intent. If both persons said "sorry it wasn't in my control", you'd think
1) the person A didn't do bad, because they have a tic and they definitely don't have negative feelings towards me
2) the person B has an anger management issues and may or may not have negative feelings towards me, maybe he's bad
We assume intent is malicious when a person has the capability to stop themselves from doing something negative towards us and yet they "chose" not to.
A CPU that doesn't work when power is off could be a good CPU, but a CPU that doesn't work when power is on is a faulty CPU.
We just established nobody chooses what they do or how they feel, so at best it's like a matter of degree and at worst it's completely arbitrary.
And "can choose to" with "can go to else{} if rx is true" - and social interaction and reward/punishment can make rx == true.
These questions are decided in legal contexts all the time, so you can look up precedent. Generally there are considerations of coercion, mental fitness, and age/experience, because your responsibility is proportional in some sense to how much you know/have learned. If you literally have never learned right from wrong, say you were raised by wolves, then you are generally not held responsible until you do (or rather, you are held responsible, but the penalties are teaching you right from wrong rather than something more severe).
> just as much as the people that you describe.
I'm not sure which people you mean. I'm saying that it is both true that you "cannot help it" in one sense and false in another sense.
There is always a causal level in which you could not have helped it. But it is never correct to conclude that there is nothing you could've done to help it, because this is also a choice and making it prevents higher-order changes.