Shared-memory parallelism is necessary but not sufficient. Ideally you'd be able to only make some small changes in a few spots to greatly increase parallelism. I'm hopeful that TypeScript's AST parsing is a good candidate since ASTs can typically be constructed independently from the rest of the program state. Lowering and printing ASTs is also likely parallelizable. It would also be great if it was also possible to parallelize parts of the type checker somehow, but that sounds harder. I had some ideas about that in another comment. Anyway I think this means that it's likely that a port of the TypeScript compiler could realistically lead to significant speedups and may even lead to extreme speedups.
As far as language choice, it sounds like due to maintenance reasons the decision space is narrowed to native, garbage collected languages similar in object model to TypeScript but with parallelism primitives. Some candidates could be at least Go, JVM-based languages, or .NET-based languages. I think those can all be ahead-of-time compiled to a static binary? Another consideration is how easy/compact/fast/cross-platform binaries are. Go makes this trivial but I haven't used JVM or .NET AOT builds myself so I don't know how they compare in e.g. executable size or startup overhead. One advantage of picking Go is that esbuild has already demonstrated that Go is an effective choice for this problem domain, which may mean less work/research/unknowns. A disadvantage of Go here might be that the object model is different than TypeScript vs. something like Java or C#. But all else being equal the choice comes down to personal preference.
I'm not sure how well supported they are / haven't used them, but I think they enable this?
You could also try sending JS objects between workers instead of using SharedArrayBuffer. But that copies the memory, which can take a significant amount of time, and of course also excludes certain kinds of advanced parallelism that require shared memory (instead of copied memory). Another drawback of using the JS worker model like this is that having multiple JS VMs probably means fewer CPU cores available due to there being multiple independent garbage collectors. I observed an effect like this when I tried to parallelize esbuild's JavaScript plugins. Running them in separate workers seemed to cause the gains from parallelism to stop when there were half as many workers as CPUs. I'm guessing is because half of the CPUs are busy collecting garbage for the other half. Using a language like Go with real shared memory presumably makes it easier for fewer resources to be spent on garbage collection.
[1] https://github.com/parcel-bundler/parcel/tree/v2/packages/co...