What are the "security enhancements" that those users are missing out on?
Those are useful mitigations, but disabling them for some custom user-chrome is unlikely to have a meaningful impact on your browser's security.
[0] https://searchfox.org/mozilla-central/source/dom/security/ns...
[1] https://searchfox.org/mozilla-central/source/dom/security/ns...
[2]: https://blog.mozilla.org/attack-and-defense/2020/06/10/under...
https://searchfox.org/mozilla-central/source/dom/security/ns...