I still use a lot of Python, often for little tools or scripts, especially anything where data needs to be transformed (like file formats for art assets), or something needs to be automated (run build scripts for all the different platforms). I built a little graphical puzzle/level editor for The Cat Machine with Python and SDL bindings too.

But I'm mostly using C# and Unity these days. There's too much useful stuff build into Unity to ignore it, and C# is very pleasant so I didn't find it particularly hard to make the jump - there's just a very definite 'Way' Unity wants you to do everything and so most of the time it's just a case of working out what that Way is.