Ryan here from YC.
There are certainly companies looking for talent that is only time-zone friendly. Having run an engineering team co-located in SF & Beijing, I know how hard it is myself to be working odd hours for standups, product syncs, etc.
That said, there are other companies that are hiring truly global. I know OneSignal is one such YC startup, having hired somebody during the pandemic in the Netherlands.
Last year alone, YC startups hired across over 40 countries. I can dig into more data re: how many were US-based companies hiring abroad -- that's a good distinction.