Only in browser. I'd be very happy to hear of an ad-blocking solution for the Android app... I mean I've heard of ad-blocking VPNs but other than that?
Firefox for Android is a pretty great client. There are also third party clients.
There are some solutions if you'rere willing to look into it. Not a 100% solution, but they work amazingly.
I'm afraid of naming them here because not sure of the repercussions
Check out YouTube Vanced. It has this and many other great features.