No longer will we need to "load" things, there'd be no reason to copy an executable or resource from the filesystem into memory to use it, it can be executed, used and modified directly where it is. This is wonderful for a great many things.
A system native to this type of memory may be divided into "permanent" and "scratch" storage. So if you create a new file, you do something of a named allocation, and operate directly in that buffer, and allocate another unnamed (scratch) buffer for the undo/redo stuff. Now there's no longer a save button, since there is only the one instance of your file. Sure, reallocation and stuff will need to be convenient, probably you could have a convenient, but that's a small issue to fix.
Then there's boot times, powering off? save PC and registers to some predetermined place, powering on: load them, and you're ready to continue, literally no boot time.. No reason to put the system to "sleep" you can power it on and off within a few clock cycles. Add a framebuffer on the display, or something like eink, together with "power up on input" and you get enourmous power-savings and battery life