It was my layman's understanding that R&D or building a new factory would count as "business expense" so thanks for clarifying that.
Sure, gross profit would not include either of those expenses. But operating profit would subtract research and development (e.g. the salaries and bonuses of the engineers working on the next process node) and depreciation on new factory (i.e. the cost of the new factory spread out over its useful lifetime - though it doesn’t include a factory under construction). Then you subtract interest and taxes to get to net profit. And TSMC has net profit margins of 39% in 2020!