I'd suggest there are no right or wrong sacrifices when it comes to these kinds of matters. You have to decide what you want most and go for that, and find a way to not dwell on the path you didn't take.
In terms of a biological clock, nothing prevents you from meeting someone, falling in love, and starting a family if you live overseas. Lots of expats meet partners and in many places, you'll find that a lot of expats with residency are married to locals.