Really hard to know. My personal experience is that whenever I do weird shit, however, I've ended up in a better place? That is also itself a weird thing. Anyway, great comment, I just don't even know how to begin knowing the truth of this one without a personal belief based on lived experience. How would you even design an experiment to find the truth of this one?
I don't think so. If you put some effort into your fallback plan, and choose your weird shit so that it's likely to work out, I think it can just be a good bet. And it's hard to imagine working up the energy to do it if you're really happy where you are, you know?