What do you mean by "won't allow"
What's "online" with a "quick response" - suppose you step away for 45 mins to work out? Is someone giving you a hard time because your response time to an email or a Slack message is not immediate? Does that question or inquiry need to be handled that quickly?
Lots of things like this seem like a failure to set expectations. We're allowed to deliberately block our calendars, right? That might mean you close your email and do an hour of work solid, or work out, or run an errand. But it's possible, with some deliberate calendar planning, and frankly transparency with those expecting something from you.
"I won't be available for the next 45 mins because [X]" is a pretty easy statement to deliver