If I get really low on sleep I’ll usually develop a cold, even if I haven’t been around anyone that’s had one in some time. I feel like there’s a lot to virology we don’t have a good grasp on.
I do a lot of scuba diving. There are many anecdotal reports of divers who briefly experience cold / flu symptoms after failing to decompress correctly. The popular hypothesis is that tiny bubbles in the bloodstream trigger an inflammatory immune response, but who knows?