I've gotten a lot of mileage out of ignoring grandstanders and focusing my time and energy on learning how browsers work. If you understand the DOM, CSS and core JavaScript fundamentals, you can apply your skills to virtually any front-end stack.
In the end, the thing that hurts the web the most is complexity in the name of DX. We are tricked into thinking that the simple thing is too hard to learn on the one hand, while being asked to juggle multiple layers of "sophisticated" abstraction on the other. These days there are entire businesses rising on the need to reduce the cognitive load created by our layers of sophisticated abstraction. But, I bring you the good word: you can still build incredible experiences without pulling in most of the complexity (and without sacrificing as much DX as you think).