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The current version of the python lib seems to be extremely badly written code. Or is the algo so bad ? Takes something like 21s to compute the correlation for just 10k samples.

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This issue contains simple code that is claimed to be >300x faster: https://github.com/czbiohub/xicor/issues/17

Thanks for locating the solution. I didn’t check the Python code myself so I wasn’t sure what was going on with the slow processing

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