It's possible to get some kind of tactile response mimicking the edges of buttons well enough. I'd say a good implementation of this technology would be safe IF the position and availability of the controls would be static. I'm not sure what you'd get out of a touch screen with those constraints (less parts?), especially with the added cost and research, but that's the only way I can see a touch screen in a car that should ever be legal.
A Tesla driver in Germany already got fined for using the touch screen of his car while driving. It's strange how this obvious flaw of a car design has ever been allowed onto the roads.