In ancient Egypt they tried to treat breast cancer with rudimentary methods around 3000 BC:

Our oldest description of cancer (although the word cancer was not used) was discovered in Egypt and dates back to about 3000 BC. It’s called the Edwin Smith Papyrus and is a copy of part of an ancient Egyptian textbook on trauma surgery. It describes 8 cases of tumors or ulcers of the breast that were removed by cauterization with a tool called the fire drill. The writing says about the disease, “There is no treatment.”

https://www.cancer.org/cancer/cancer-basics/history-of-cance...