If you're going 75mph, that should really get your spidey-sense tingling. At least let off the accelerator/cancel cruise control. Be prepared to brake. Once you're closer and lined up, it's harder to tell there's anything going on because you're no longer approaching a bend with headlights on the other side of the truck, so by then it's too late.
But this is, again, all hindsight talking. In the moment, it's much harder to assess how a "typical human" might have reacted, if at all.