How did humanity ever survive this long without modern medicine?
In the meanwhile, the plagues and their knock-on effects may have eliminated approximately HALF of the entire population of their times.[0]
0: https://en.wikipedia.org/wiki/Black_Death ("is estimated to have killed 30 percent to 60 percent of the European population")
The question was about a world without modern medicine. It's totally reasonable to speculate there would be a higher fatality rate without medical intervention keeping people from dying.