> mRNA vaccines did basically happen overnight, yeah. As recently as 2017 they couldn't progress beyond animal trials because all mRNA based drugs became toxic after multiple doses. Better hope they nailed that problem, right?
Please, provide some sources. A quick google search led me to https://www.statnews.com/2017/01/10/moderna-trouble-mrna/ but this excerpt is in moderna's favor:
> But the Crigler-Najjar treatment has been indefinitely delayed, an Alexion spokeswoman told STAT. It never proved safe enough to test in humans, according to several former Moderna employees and collaborators who worked closely on the project. Unable to press forward with that technology, Moderna has had to focus instead on developing a handful of vaccines, turning to a less lucrative field that might not justify the company’s nearly $5 billion valuation.
> “It’s all vaccines right now, and vaccines are a loss-leader,” said one former Moderna manager. “Moderna right now is a multibillion-dollar vaccines company, and I don’t see how that holds up.”
Considering work on mRNA vaccines started in 1989 https://en.wikipedia.org/wiki/MRNA_vaccine#Early_research I'd say you are wrong. 2004 and 2008 saw the first use in a humane body of mrna transfer into the cell. Moderna may have hit a roadblock for their cancer therapy in 2017 but that doesn't mean they started working from scratch on mrna vaccines in 2017.
> As for trials, there were a lot of serious problems with the trials. A girl in the children's Pfizer trial who was maimed so badly she's now confined to a wheelchair was recorded as having "abdominal pain".
I am surprised antivax aren't running with this story. I read a bit about it and among major outlets only Fox News ran the story. But here's the thing: one case ?
> The trials reported 95% effectiveness and no need for any boosters, which turned out to be false almost immediately once the trials ended and the vaccines went to market.
Are you referring to the second dose as a booster ? I seem to remember moderna and pfizer always were 2-doses vaccines. And there were headlines and talk about whether or not it would provide a lifetime protection or regular doses. Against wuhan strains the vaccines held up their 95% protection. So what exactly is false there ?
> Maybe you have doubts and you'd like to review the underlying data? FDA only needed 100 days to read it and approve, but to release those docs to the public will take more than 50 years.
> Reality is that signing up to be a healthcare worker, now means you are at the mercy of government agencies that have a track record of bad medical practices like vaccinating people who don't need it. Not a pleasant place to be.
I don't know what track record of bad medical practices like vaccinating people who don't need it you are referring to. Previous vaccination campaign or covid vaccination campaign ?
Anyway, there are other vaccines if you rather go with J&J and Az which are traditional technologies.