It would be good to eventually see some comparisons running some average/unoptimized code. IME benchmarks seem to focus on either the very basics, or select areas where they are faster than other apps. This is important to cover, but having something that's closer to a real app is more convincing, even if the performance margins drop somewhat.

To come back to the average code. I may start an app and try to optimize things as much as reasonable. Eventually, I'm only able to focus on the functionality and a slide in performance can happen. As more developers are added, this can happen more quickly in the average organization that focuses primarily on functionality. Of course, we should analyze the perf problems and improve the code, but projects like yours may offer a huge perf boost for teams that are struggling here.

I love Python, but I've always enjoyed that bit more scope that the .NET platform provided around performance when code was less optimal. If you can really speed up WSGI this much it'll be a huge boon.