I've been super interested in trying Psilocybin as an long term anti-depressant. Looking forward to more research coming out on this topic.
I utilize both micro and macro dosing and would recommend it wholeheartedly to anyone. If you or your family have had histories of serious psychotic disorders, bipolar, schizophrenia, etc... it can potentiate that - tread carefully - but otherwise I give the thumbs up.