Have you tried AppleScript scripting? You can glue applications together and even use JavaScript if you’re not a fan of AppleScript
So with that runtime you could easily just write whatever would happen if you press which key combo (or do cronjob-like things managed by the runtime) and then write what happens inline.
Write it all to a single script, copy it to a coworker's computer, run it, several dozen key combos just work now.
That's something I couldn't manage to pull off in AppleScript or Automator, but then again maybe I was just too dumb.
I also really like Hammerspoon. The desktop automation scene on macOS is strong.