I have evaporative dry eye caused by meibomian gland dysfunction (MGD). In short, my tears evaporate too fast because my eyelids don't produce enough of the lipid part of tears.
I used to have occasional symptoms of dry eyes without knowing what it was. It all changed after I got LASEK (a bit different from LASIK, but the ultimate goal is the same) about 2 years ago. It's not clear whether LASEK contributed to my condition, or whether it was a coincidence, but my life changed afterwards.
I used to have days when I was physically unable to look at a computer screen, due to the discomfort (burning sensation) and photophobia (light from the screen would look really uncomfortable).
Right now I've adjusted my life and equipment to make living and work more bearable/comfortable. I also got a bit of medical advice/help.
Posting a short summary of what helped and what didn't, in case someone else will find it useful. I've tried so many things, so I might have omitted something.
What helped:
- Changing displays: now I'm using BenQ EL2870U (I went through multiple "eye-care" and non-eye-care displays before I settled on this one). I'm using low-blue-light configuration in the display as well as in macOS. I'm really sensitive to displays with PWM (e.g. 16" MBP). On my OnePlus 7T Pro I switched to DC dimming, which seemed to help too.
- NuLids (https://nulids.com/). It's a "massager" for the eyelids, which stimulates meibomian glands and cleans the eye lids. Both the device and the tips (I boil them and reuse them several times) are a bit pricey but I did feel the difference.
- Sleep position: make sure your eyes aren't pressing on the pillow, as this can prevent them from closing or create unnecessary pressure on the eye/eyelids.
- E-Ink displays: these are good to look at, but hard to do useful work on due to poor refresh rate. I'm using them for reading only (I have Dasung 13.3" monitor and Boox Max Lumi).
- Natural light in the room. There seems to be something about natural light that makes my eyes feel more comfortable when in front of a screen.
- Preservative-free eye drops targeting the lipid tear part (only for short-term relief, but sometimes that's needed).
Not sure whether it helped:
- IRPL (E-Eye). I'll have the 4th treatment soon, but it's hard too judge this because of other parallel things I'm doing (like NuLids). My eyes feel quite good for several hours after a treatment, but then they're back to the usual state.
- Diet (Omega 3, Vitamin A, vegetables, etc)
What didn't help:
- Optimel Manuka Honey Eye Drops/Gel. Some people said that these were revolutionary for them, but my eyes at first felt better and then I got horrible swelling and redness.
- Blue light glasses (I've tried ~10 different brands, including the more expensive and "science-based" ones (Gunnar, BLUblox).
What I want to try:
- Omega 3 supplements with higher EPA/DHA ratio (like PRN Dry Eye Omega)
- Autologous serum eye drops. I can't find anyone who can produce them in my country, but I'm thinking about getting them from abroad.
- Computer glasses for relaxing eye muscles (as mentioned in other comments).