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You can still do "-site:spam.com".

For sure! Thanks for the reminder. There was a point (as you may know) when the domains were saved into your profile, so you didn't have to add it.

I didn’t know.

When they removed the domain blacklist feature search went down hill fast.

This works, but bad actors like pinterest have found a way around that by having a domain on every TLD and ccTLD out there.

I found out by experiment that wildcards work, e.g. -site:pinterest.*