I once did a project which involved migrating an ancient (early 1980s) DOS based application to FreeDOS via a VMWare host. The application controlled an oven in a soft drinks bottling factory and due to EMI, the physical disk had to be cloned every 6-9months to avoid corruption, and sourcing ancient IDE drives was problematic.
The manufacturer was happy to provide updated software, but only alongside a new oven, at a cost of £1 million.
The factory had 4 ovens.
VMWare + Windows 7 + SSDs + proper Siemens industrial PC = much cheaper hack!
Definitely a cool feeling knowing the solution might be in place another 20-30 years :-)