No.

There is precedent in various US states and a handful of countries.

Cost benefit analysis of what is actually happening in these places is a key motivator for the continued wave of legalization around the world.

This is much studied.

DYOR but here's a start:

https://en.wikipedia.org/wiki/Drug_policy_of_Portugal

https://scholar.google.com/scholar?q=portugal+drug+policy&hl...

Also, I'm not sure if you literally mean "a few orders of magnitude" or are using that phrase to simply mean "an increase".