I see it differently: despite alcohol having absolutely horrible safety profile the vast majority of people manage to use it responsibly and don't let it ruin their lives. We all know that some people become alcoholics and yet it stops virtually nobody from enjoying Friday beer.

The drug prohibition made it difficult to know how many people use drugs responsibly. It is linked to legal weed actually: it is being legalized not because research showed it is not too dangerous (we knew it for a while), but because more and more people become aware that you can totally use weed and remain a respectable member of society.

For me it is a question of personal freedom. Everything has risks. Going hiking in mountains can kill you, for example, or almost any outdoor activity really. And some people die there pretty much every day. But I really don't want the state banning it just because some people fuck up.