There certainly can be, and have been, surprising drawbacks from what would've seemed like a clear win safety technologies.
For example ABS increased crash rates for a good while when it was new, contrary to all expectations.
From this NHTSA report: https://crashstats.nhtsa.dot.gov/Api/Public/ViewPublication/...
"Analyses of data from the early 1990s showed significant increases in fatal run-off-road crashes with ABS, on the order of 28 percent. The increase was baffling, given the success of ABS on the test track. However, at that time, many drivers did not yet know how to use ABS correctly."
I observed this effect first hand, because from the late 90s to the late 00s I was frequently a car control clinic instructor. One of the exercises of these clinics was to teach panic braking. In the earlier years most people showed up with non-ABS cars so this was a great exercise in teaching proper braking control.
As ABS cars became more and more prevalent we (the instructors and the school) thought that this exercise can go away since there is no skill to learn braking if you have ABS, just mash the pedal.
Alas, no! It is difficult to believe, but approximately nobody that came to these car control clinics with an ABS car was actually able to initially brake hard enough to even activate the ABS. Sometimes it took many many runs through the braking exercise to finally get it: just press hard on the brake pedal.