Having written both Haskell and Scala professionally, I actually see Scala's dependence on the JVM as its biggest flaw.

If it weren't for the JVM Scala could make do without an Any type and without having to deal with null values. I hope that alternative runtimes like Scala Native will become more popular, since Scala could evolve away from its JVM roots then.

I'm also not a fan of JVM performance optimization, since there are too many knobs to turn, and the knobs often have (undocumented) side-effects on other knobs. This is a lot simpler with the Haskell runtime (in my experience) since you mainly need to tweak the GC settings there.