Here's some work I and others did earlier this year, which I thought was a great example of folks from the core Python packaging world and folks from distros working together: https://www.python.org/dev/peps/pep-0668/ See the massive table of use cases for all the things we had to think about.
You might note that one of the things it needs is additional participation on the Discourse thread from the authors (like myself) and from other distros. Again. It's mostly work done by volunteers, and there's a lot to work through. There's no magic to it.
I can tell you that the following (from TFA) will absolutely make things worse for distros, though:
> I call on the PSF to sit down for some serious, sober engineering work to fix this problem. Draw up a list of the use-cases you need to support, pick the most promising initiative, and put in the hours to make it work properly, today and tomorrow. Design something you can stick with and make stable for the next 30 years. If you have to break some hearts, fine. [...] These PEPs are designed to tolerate the proliferation of build systems, which is exactly what needs to stop. Python ought to stop trying to avoid hurting anyone’s feelings and pick one.
If you want the PSF to fund some engineering work on its own that it can finish much faster than any volunteer packager can even read the proposal, break some hearts, stop proliferating build systems, and hurt people's feelings, they will absolutely do that and say "Distro packaging is not supported, we only support virtualenvs. Users should make virtualenvs. Distro software should ship virtualenvs. Installing a Python package systemwide is meaningless." That's clearly the best-supported option right now, and it's a surprisingly technically defensible answer, but it's not going to make you happy.