Fermi did not think that aliens would get past the speed of light, but what we have found out in the last 40 years does make his paradox less striking. If Fermi was alive today I expect he would not have wondered "where's everyone?" Instead I think that he would be saying that there's a range of reasons why intelligent life is vanishingly rare. The dynamics of most solar systems (big planets migrate in) and the role of Jupiter as a comet catcher as well as the insights into the history of life and the miracle of the eucaryotic cell.