It's possible that the full experience with a trained therapist who supervises the trip could produce longer-lasting changes, of course.
Personally, I think the best option is it gets mainstreamed by knowledgeble guides working with individuals through the process, the mushroom growing is done by small-scale growers who do it with the passion and love this Medicine deserves, and the pill-makers are kept far and away from it.
In general it doesn't has to be, but in this case the research is done by a for-profit company which expects to see a return on their investments.