No crypto expert but I was thinking something like this:
Artist decides to make a run of 100 copies of the work, and generates 100 work signing keys and generates a list of "1/100, work public key 1" etc. Artist then signs this list with their artist signing key, gets a signed timestamp, and publishes this somewhere on their site, along with the public portion of their artist signing key.
Artist then signs the (uncompressed) pixels of each copy of the work using the corresponding work signing key. Signature is embedded in the image file along with the work copy details, "1/100", say as a PNG chunk or similar.
NFT is created for the work copy, and I'm presuming there's something akin to a signature of the image file in the NFT to link them.
If you then get a NFT you can verify that the image file is indeed what the NFT refers to. You can download the work public key from the artist and verify that the public work key is from the artist, and then verify that the work (pixels) is what the artist signed.
Then again I don't know the domain enough so might be completely silly and or flawed idea. And obviously it requires a non-lossy image format ala PNG.