Well, it may be that type 2 diabetes has the same mitochondrial roots. Specifically, the oxidative phosphorylation pathway gets wrecked in T2DM. This produces ROS. A lot of ROS, and it looks like the very same defect occurs in long Covid patients. And some of them become type 2 diabetics out of nowhere.
But. I was able to observe, diagnose and treat one person with such condition. She had Covid in August 2020, then vaccinated in 2021 and had the second Covid in August 2021. All episodes were not severe, just usual cold.
During the second Covid, at the very start of illness, she started to develop the signs of POTS. She was administered B1 TTFD, B3 Nicotinamide Riboside, multivitamin, D and C. POTS quickly resolved in 1 week. After that, I had a hard time talking her to continue the medications. She believed that she was strong enough already.
All went seemingly well. She totally got well and fully recovered. On occasional walk I told her about mitochondria, ATP synthesis, electron transport chain, suffering people with burning feet and hands, just for kicks. She told me that I was a mad scientist, that all such diseases are designed by nature to make the Darwin selection work etc. And that I should not really care as people are not able to value that.
The next day we were amid a walk again and that time it was 12 km (7.5 miles) distance. In the middle of the route, she had her first panic attack. All of a sudden, her breath rate increased significantly (hyperventilation) and face were starting to cover in large redish blumishes. She then told me that her knee muscles are going to collapse (miopathy) and she may fall. She felt the need for sugar and water. We were able to go into gas station and get a sweet snack. I estimated the volume corresponding to 15 g of sugar and gave it to here. Panic attack had stopped like it did not happen at all.
Most people will be puzzled by this situation, but it was clear as day to me. Her oxidative phosphorylation pathway got inhibited and she became unable to consume the usual levels of glucose from the blood. Her ATP production was down. When ATP production became critically low, the nervous system began to panic and the endocrinal and cardiovascular systems entered into compensatory state, trying to increase oxygen saturation (hyperventilation), the bloodflow (tachycardia) and glucose levels to overcompensate the ever decreasing ATP production. Once she ate 15 g of sugar compensation of ATP production was reached and she stabilized. Attack was stopped right there. She had a stroke of false hypoglycemia and it was resolved now.
Important observation - this occurred during the long walk which depletes ATP faster due to physical load.
Next morning, I measured her blood glucose level. She went into diabetic area (7.4 mmol/L), despite having an absolute healthy glucose levels (5.2 mmol/L) months before.
I immediately suggested the therapy targeted on mitochondrial ETC. B1 TTFD, B3 (Nicotinamd Riboside), Multivitamin Complex, C, D. This time, I extended the list of supplements with Q10, alpha-lipoic acid, L-Carnitine and Benfotiamine given the seriousness of situation.
Her glucose uptake were gradually improving. After 3 weeks of therapy she had 5.5 mmol/L fasting glucose level which was healthy and totally fine. No diabetes.
We continued with that route for 1 more month, then gradually downgrading to Q10, alpha-lipoic acid and B1 (100mg HCL supportive dose). She was on stable 5.2 mmol/L fasting glucose levels which is excellent.
Currently she is on Q10 60 mg + B1 HCL 100 mg every other day. No signs of regression. We will drop the medications in month or two.
Was I able to treat the diabetes? Probably no. What I've treated is a long Covid syndrome that could lead to diabetes and variety of other induced pathologies.
Why? Because science frees from suffering and I like to help people, despite all their flaws.
I hope that someone somewhere will find this information helpful.