A new thought: you'd think people back then would just see that it was safe because Italians were eating it and not dying. But then again we seem to still live in an age where facts about what things are safe to take are still under siege.
> In 1602 an anonymous English author published an essay titled Worke of Chimney Sweepers (sic) which stated that illnesses often seen in chimney sweepers were caused by soot and that tobacco may have similar effects. This was one of the earliest known instances of smoking being linked to ill health.
> In 1795 Sammuel Thomas von Soemmering of Maine (Germany) reported that he was becoming more aware of cancers of the lip in pipe smokers
> In 1798 the US physician Benjamin Rush wrote on the medical dangers of tobacco
Closer to home, within the twentieth century, Max MacLevy’s book "Tobacco Habit Easily Conquered” (1916) was well known, as was Louis L. Krauss’ "Tobacco Mysteries Exposed and Habit Conquered” (1917).
Krauss lists the available evidence as to the known dangers of tobacco for almost 100 pages. This was in 1917. We also know that the public was exposed to much of the information in Krauss’ book. I haven’t even brought up the Germans.
Any cursory review of the the history and harm of tobacco shows this is true. Your counterargument is just wrong, and given its latest iteration, has now devolved into no true Scotsman.
> It's generally not permitted in pharmaceutical products, some countries restrict its commercial sale
It's never been acceptable as food. Only as a mislabelled pharmaceutical product. That ended in 2002 after some nonsense in Germany.
My grandma had decided to do something wild and new and had made one of those newfangled frozen pizzas for dinner, kids loved those she'd read.
So we sat down, each getting a slice, and then she serves my grandfather a small plate with three cooked potatoes on it...
I ask what's the potatoes are for.
"It's not dinner if there's no potatoes".
And with that, he ate pizza with potatoes.
This is mostly anecdotal, but I've had something similar happen in Nicaragua. Most of my acquaintances and friends don't consider pizza a "meal". It is considered by most only a side dish, because it doesn't come served with rice