I'm not sure how many man-hours were lost to fatfingering :wq as :Wq or :w as :W, but a simple alias has solved that particular bit of grief:
cnoreabbrev Wq wq
cnoreabbrev W w
The rest of my .vimrc mostly belongs to the guy I caught the vim addiction from, but sets some useful defaults: https://github.com/duggan/dotfiles/blob/master/.vimrc