This raises an interesting point in general in any area where consciousness is taking more control over things that have always been subject to unconscious nature.

In this case, when natural conception results in deformity, genetic illness, or just generally unfit offspring, there's no one to blame. I suppose you can get mad at God, but we have yet to figure out how to sue them.

But when human actors start making choices that nature previously made, suddenly, we have someone concrete to blame when things go wrong, even if things go wrong much less often and less severely.