The days of needing a tower are over for most people. I'm all about space-saving while still having a full-power PC.
It's a niche, boutique market but there are some really interesting cases. My personal favourite is the Louqe Ghost S1 [1]. I've built one PC with this (the Mk II). I bought a Mk III case but couldn't source a GPU so ended up just buying a CyberpowerPC prebuilt (which is actually a pretty nice PC, to be fair).
They're not cheap and they're kind of annoying to buy. Louqe in particular has had huge distribution problems in the US (through Amazon's logistics service).
Another popular one is the Dan A4 [2]. It's smaller. I personally prefer the Ghost for having better airflow, being more modular and being able to expand the case with "top hats". This allows you to add a 240mm AIO and bottom fans for some pretty darn good cooling and airflow.
Anyway, I'm always excited to see entrants in this market.