the one that does my head in is you can search for a file with spotlight but then the only thing you can do with the result is open it; you can't see what folder it's in or open the folder.
Hold down Command (or maybe Option), and it shows you the full file path in the bottom of the preview pane.
View > Show Status Bar
You can click on any of the folders to go there.
In spotlight, cmd click on the file to show it in the finder.