An interesting tidbit about tomatoes, and other nightshades: They contain nicotine!
Based on which metric? Neither vanillin nor capsaicin are tropane alkaloids.
Tropane structure of cocaine, scopolamine make them accumulate in liver whereas vanillin, capsaicin etc do not accumulate.
Scopolamine stramonium etc are fascinating too. Datura stramonium (DS) is a widespread annual plant, containing atropine, hyoscyamine, and scopolamine, which can produce poisoning with a severe anticholinergic syndrome. In some parts of the world, ingestion of the roots, seeds or the entire plant is a trick to obtain its hallucinogenic and euphoric effects.
Also was used to poison royalty and by dacoits. It also has medicinal properties. Has been recorded in medical textbooks at the time of Takshila university and in Buddhists texts. Very effective as homeopathic preparations. Jimson weed is still a common weed on road sides in America. Datura is in the same family of plants as peppers, tomatoes, potatoes and eggplants and it contains a lethal set of alkaloids. But they don’t have the same kind. Tomatoes, for example, doesn’t have any alkaloids. Only tomatine.
There's one study hypothesizing that glycoalkaloids can increase/aggravate intestinal permeability (which is a real thing), but this study only looked at mice [1]. The hypothesis has not been rigorously tested in any serious clinical study on humans.
The food elimination diet is very scientific - you add items back in one at a time to test if they cause a negative reaction to your particular physiology.
Most boring month ever. Felt amazing at the end of it.
Was shocking when I introduced things back in.
Chocolate and “diet” drinks turned out to be massive migraine triggers for me. That was a big surprise
But it is a trade-off. Apparently I got "tomatoes taste good" in return for my "cilantro tastes toxic."