While I like the basic premise of embracing the uncertainty, I disagree that "nature" (evolutionary model) is the approach to follow: while it has produced marvelous results, "experiments" took way too long to learn from if they were progress/success or not.

I think we should embrace experimentation, but we should improve on natural processes because we are smart, sentient beings, and there are things we can predict and measure much faster, and thus pivot much faster too (as an example, all genetic diseases that are commonly terminal after the early reproductive age in humans are likely to be carried on into descendants because, well, reproduction has already happened — it would take many generations for "nature" to weed out those diseases, but luckily, we've got medicine that helps us not even having to weed them all out, and does stop some altogether).